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Manjishta – Rubia cordifolia – Ayurvedic Herb

MANJISTA

Rubia cordifolia – Ayurvedic Herb

 

 

MANJISTHAS - Rubia cordifolia - Ayurvedic Herb

 

 

Manjishta’s anticedance dates back to vedic period. In Aitereya Aranyaka is described. During upanayana samskara ksathriyas are expected to wear the cloths coloured with “Manjishta”. It is known as artificial colouring agent from the beginning. However, Ayurvedic texts emphasized its role in medicinal usage.

Charaka described it as Jwarahara while sushrutha mentioned it as Pitta Shamaka. All the texts have delineated it as the herb useful to improve the colour and complexion of skin. It is famous as Rakta Shodhaka (blood purifier) in the traditional medicine.

At present it is used mainly as natural colouring agent in the fabries industry. Current research revealed that Rubia cordifolia is a potent anticancer / antitumour drug.

In vaidya chinthamani , manjishta is enumerated among the ‘Kanda Sara’ dravyas . Therefore it may be concluded that ‘root’ is the useful part in ‘Manjishta’.

  • Botanical source is Rubia cordifolia Linn.
  • Family is rubiaceae
  • Sri Chunekar KC reported that Rubia cordifolia is an adulterant for ‘swertia chirata’.
  • It is also reported that Oldenlandia umbellate or Hedyotis hispilla or Hedyotis indica is an adultrant for ‘Manjishta’.

 

VARIETIES

 

  • Rubia tinetorium Linn: ie, Acc to Gangadhara (C.S. Su. 4); Srikanthadatta (Si. YD.65/141); Dalhana (S.S.Sa. 10).

 

  • Ramakanta Manjishta ie, Acc to Bhoja (Bha. Pra. Nirukta Yoni roga).

 

 

SYNONYMS

Manjishta : Has pleasant colour, Provides good colour.

Yojanavalli : It spreads to long distances along with its good

qualities.

Raktayashtika : Stem is red in colour.

Raktangi : The roots and other parts are red.

Rasayani : It has rasayana property.

Vasthraranjani : It is used for dying fabric.

Vikasa : Spreads along distances.

Samanga : Spreads in all directions.

Kaalameshi : It fights against aging.

Chithraparni : Leaf base is cordate.

Jvarahanthri : It cures fever.

Thamramoola : Red coloured roots.

Bhandi : Provides good complexion.

 

VERNACULAR NAMES

 

  • English – Indian Maddar
  • Hindi – Manjetha
  • Kannada – Manjishta
  • Malayalam – Punta
  • Telugu – Manjishta
  • Tamil – Manjetti
  • Marathi – Manjth
  • Bengali – Manistha
  • Gujarathi & Punjabi – Majith

 

PARTS USED

  • Root

 

 

MAJOR CHEMICAL CONSTITUENTS

 

  • Anti tumor cyclic hexapeptides RA-V and RA-VII along with RA-I-IV.
  • Anthraquin ones munjistin.
  • Purpuroxanthin, rubiatriol, rubicoumaric acid.
  • Rubifolic acid.
  • Pseudoparpurin, alizarin, rubiadin, rubimallin, purpurin, xanthopurpurin, ruberythric acid.

 

PROPERTIES

  • Rasa : Madhura, Thiktha
  • Guna : Guru, Ruksha
  • Virya : Ushna
  • Vipaka : Katu
  • Doshaghnatha : Kapha – Pittahara
  • Karma : Varnya, Vishaghna

 

YOGA

  • Maha manjishtadi Kvatha : (B.P.N)
    • For tvak dosha, 18 varieties of
    • Also useful in vatarakta , prasupthi, Visarpa, constipation, blood disorders.
  • Laghu manjistadi Kvatha : [BPN]
    • In Vatarakta, Kandu, Pama, Raktamandala, dadru, visarpa, visphota.
  • Madhyama Manjistadi Kvatha; [B.P.N]

Vatarakta, kandu, visarpa, Visphota.

  • Sindhuradi Taila : [B.P.N]

Useful to get rid of Pama.

  • Adityapaka tailam:

Oil is very useful to get rid of pama.

  • Pancha thika guggulu ghritha

Nadivrana, arbuda, bhagandhara , gulma aruchi, svashana, peenasa, Kasa, vatarakta.

  • Nava Kashaya: [Vangasen]

Indicated in kushta caused by Kapha & pitta.

  • Pinda taila: In vatarakta.
  • Manjishta Lepa: Mixed with shatha dhoutha ghrita & applied over Bhagna pradesha.

 

 

KARMA

  • Rakta prasadana – Raktashodhaka [K.N], [B.N]
  • Varnya – tvachya. [Kaiyadeva. N] [Bhavaprakash .N]
  • Mastika- Nadishamaka.
  • Dipana-Pachana- amapachana. [K.N], [B.N]
  • Stambhana [Kaiyadeva. N]
  • Krimigma [Kaiyadeva.N]
  • Kaphagna [Raja. N]
  • Garbhashayottejaka- Artavajanana [Kaiyadeva. N]
  • Stanyashodhana [Kaiyadeva. N]
  • Pramehaghna [Kaiyadeva. N] Bhavaprakasha.N
  • Kushtaghna [Bhavaprakasha.N] [Kaiyadeva.N]
  • Jvaraghna [Bhavaprakasha.N]
  • Balya- rasayana [Baiyadeva.N]
  • Vishaghna [A.H. Uttara 36-59]
  • Shothahara [ Rajawallabha.N]
  • Arshoghna [Kaiyadeva.N] [ Bhavaprakasha.N]
  • Sandhaniya [Vrindhamadhava, 46-3]
  • Svarya [Raja. N. Pippalyadi Varga]

 

PRAYOGA

  • Kushta [Kaiyadeva. N]
  • Charmavikara [k.N]
  • Vrana- Visphota- Visarpa-Pidaka [K.N. D. Ousadhi varga]
  • Kshudraroga – Nilika – Vyanga [Charadatta.K.1191-93]
  • Arshas [K.N]
  • Visha –Sarpavisha – Astanga. H.Uttara, 36-59.
  • Prameha- Manjishtameha [K.N], [B.N]
  • Agnidagdha [Chakradatta]
  • Bhagna [Vrindhamadhava, 46-3]
  • Shlipada [K.N]
  • Shotha [ Rajavallabha.N]
  • Muthrakrichra [Rajavallabha. N]
  • Agnimandhya – Amadosha- Atisara [K.N] [B.N]
  • Krimiroga [K.N]
  • Raktasrava [K.N]
  • Kasa-Svarabheda [R.N. Pippalyadi varga]
  • Kashtartava – Rajorodha [K.N]
  • Prasavottara vyapat- stanya shuddhi [K.N]
  • Jvara, Dourbalya. [B.N]
  • Akshi- Karnaruk. [K.N, Oshadhi. V] [B.N] [Chakradatta]

 

PHARMACOLOGICAL STUDY

 

Haemostatic effects

Anti-platelet aggregation.

Leukogenic effect; By carboxylic acid glycosides with aromatic rings.

Anti sputum effect

Anti carcinogenic effect

Urinary Calculi effect

Myocardial infarction treatment

Effect on smooth muscles.

 

FLOWERING AND FRUITING TIME

 

Plant flowers during rains or July. September, and its fruiting stage begins onwards. ie “September- November”.

 

THERAPEUTIC USES

 

  • Gynacological problems like white discharge and irregular menstruation.
  • Manjishta meha; Manjishta and candana kasaya is useful [S.S Ci 11/9].
  • Arsas ; In bleeding piles ghee prepared with manjishta and sigru should be given. [S.S. Ci6/9]
  • Kandabhagna : Manjishta and Madhuka are made into paste using amla dravyas and applied externally [V.M]

 

FOLKLORE USE

 

o It s paste should be applied in various skin disorder like itching, black spots on the face, pimple, leucoderma etc.

o Decoction of Manjishta cures various skin disorders & blood disorder.

 

RESEARCH STUDY

 

  • Rubimallin showed antibacterial activity [yaoxue Yuebao 1990, 25, 834].
  • Antitumour cyclic hexapeptide, RA-VII from Rubia cordifolia is reported [ilokawa et. Al. 92]
  • Four napthohydroquinones and two naphthohydroquinones from Rubia cordifolia and their cytoloxic activity are reported [Itokawa et al. 1993]
  • Anti tumor activity of RC-18, a pure isolate from Rubia cordifolia was reported [Adwankar & Chitnis, 1980 & 1982]
  • The anti –peroxidative property of Solvent free alcoholic exhact of Rubia Cordifolia has been studied in rat liver homogenate. It prevents the eumene hydroperoxider induced malondialdehyde formation in the does & time dependent manner. This effect is accompanied by the maintained reduced glutathione level even in the presence of above toxin [Pandey et al. 1994]
  • The blood purification effect of the partially purified fraction of this whole plant has been studied on rabbit platelets. It inhibits the platelet aggregation induced by PAF [ Platelet activating factor] but not thrombin. It also inhibits the binding of 3H- PAF to the platelets in the dose dependent manner. Thus it appears That R. Cordifolia inhibits action of PAF at its receptor level either by its blocking or by desensitization [Thripathi et al. 1993]
  • The napthohydnoquinone suppressed the secretion of hepatitis B surface antigen [HB s Ag] in human hepatoma hep 3B cells [Ho et al. 1996].

 

DOSAGE

 

Powder [ churna] : 11 – 5 g.

Kvatha [Decoction ] : 50 -100 ml.

Solid extract [ with water] : 150 – 540 mg.

Dried extract [ With water }; 105-315 mg.

 

NON MEDICINAL USE

 

Manjishta is used as colouring agent in fabric industries.

During upanayana samskara the kshatriyas are expected to wear the cloths coloured with Manjishta .

It is known as artificial colouring agent from the beginning.

Mandukaparni – Centella asiatica Linn – Ayurvedic Herb

Mandukaparni

Centella asiatica Linn – Ayurvedic Herb

 

 

 

mandukaparni ayurveda

 

 

 

The drug manduki is known since the vedic period and is considered as one of the important aushadi.

Charaka described it as medha rasayana and the same is accepted by all the ayurvedic texts.

There are certain herbs with similar names which need to be differentiated from mandukaparni viz, mandukaparna is syonka and mandukaparnika is manjustha.

 

SYNONYMS AND INTERPRETATION

  • Mandukaparni :- its leaves resembles the shape of the body of frog.
  • Mahaushadi:- it is a potent medicine for imprailing intelligence.
  • Sarasvati:- its rasa is potent.
  • Mandiki:- it is a runner.
  • Twasti:- it is the site for goddess lakshmi.
  • Divya:- it is a divya aushadi as it has devine.
  • Suvarkata:-
  • Adithya bhaktha:- gives brightness to the mind like sun.
  • Mandukabrahmi:-
  • Somavalli:- a creeper having the properity of soma.
  • Brahmi:- a plant looks beautiful.
  • Smarani:- improves rememberance capacity.
  • Darduro:- like a frog prefers marshy place for its growth.

VERNACULAR NAMES

  • English:- Indian penny wort.
  • Hindi:- brhamamanduki.
  • Kannada:- brhammisoppu, vandelaga.
  • Malayalam:- muttil, kutannal, kadanghal.
  • Telugu:- sarasvathyaku.
  • Tamil:- vallari lirai.
  • Gujurati:- kjanda brhami.

OFFICINAL PART

  • Whole plant

 

DOSAGE

Swarasa:- 10-20ml.

Choorna:- 3-6gms.

 

CHEMICAL COMPOSITION

  • Fresh leaves contain a glucoside asiaticoside and asiatic acid.
  • Root and leaves contain vellarine, pectic acid and resin.
  • Plant contains alkaloid hydrocotylin, a white crystalline, bitter, medicinally potent principle, volatile oil in little quantity.
  • Dried herb contains centoic acid and centellic acid.
  • Leaves rich in carotenoids and vitamin-B&C, flavanoids.

 

PROPERTIES

  • Rasa :- Tikta.
  • Guna:-laghu.
  • Veerya:-sheetha.
  • Vipaka:- Madhura.
  • Doshaghnata:- kapha, pitta, shamaka.
  • Prabhava:- medhya.

 

CONROVERSIAL STUDIES

 

  • Mandukaparni and brhami are often confusing the scholars.
  • Bhavamishra prscribed brhami mandhukaparni as possessing similar properties.
  • Dalhana:- several times quoted mandukaparni and brhami as synonyms. But measured these two plants separately under rasayama chapter.
  • In dhanvantari nighantu and raja nighantu suvarcata is used as synonyms of mandukaparni.
  • Shodhala described its as mandhuka brahmi.
  • Kaiyadeva identified both these plants synonyms after a long controversy, at present mandukaparni and brhami are identified as centella asiatica and B. monniere respectively.

 

THERAPUETIC USES

  • Apasmara:- Brhami swarasa with dugdha is given.
  • Unmade:- brhami swarasa and kusta and given along with honey (V.S)
  • Udhara roga:- mandukaparni shaka and trivrut is given along with swarasa.
  • Masurika;- brahmi swarasa with honey.
  • As a general tonic rasayana. Swarasa is given along with milk.
  • Kamala:- mandukaparni juice is mixed with the honey. Haridra, amalaki or milk and taken in the morning. (vai. Ma)
  • Pitika:- applications of mandukaparni juice locally with be useful (G.N).

 

RESEARCH STUDIES

  • In a double blind clinical trial on thirty mentally retarded children, a significant improvement in both general ability and behaviourial pattern when the drug was administrated for a short period of 12 weeks.
  • In a double blind clinical trial on 43 normal adults, the rasayana effect of the drugs was studied. It increased the mean level of RBC, blood sugar, serum cholesterol, vital capacity and total protein. The increase is 116% was quite high and statistically significant. The drug also decreased the mean blood area level and moderate decrease in serum acid phosphate was observed(appar rao, A69).
  • The whole plant powder prevented the mortality rate and albino rate feed on low protein diet it increases the blood protein nitrogen and prevented the fatty infiltration of liver(rajagopalan et.al .1970).
  • Titrated extract of centella asiatica revealed good therapeutic effects on peptic ulcer.
  • Brahmosides were found to posses sedative action in rats equivalent to that of a minor tranquillizer. The action appeared to be mainly on the cholinergic mechanism.

FORMULATIONS

 

  • Brahmi rasayana:- charaka chikitsastana, B.P
  • Saravatarishta:- yoga rathnakara.
  • Brahmi paka:- bhava prakasha, Y.R
  • Brahmi gritha :- Y.R.
  • Brahmi taila :- Y.R.

 

FOLKORE USES

 

  • Leaf juice with palm jaggery is given to women as a tonic after delivery.
  • Syrup of leaves with ginger and black pepper is taken for cough.
  • Leaf juice is rubbed on the forehead to cure haead ache.
  • Leaves are diuretic.

 

ECOLOGY

 

It is commonly grows in marshy areas throughout India, Nepal, srilanka, china, Taiwan and vitah, and is also found in florida, Hawaii and other southern states of USA. Where it can be grow in common conditions by the pond or bog garden.

 

CULTIVATION AND HARVESTING

 

Cultivation:- cultivated throughout the India especially Bombay and Bihar.

Harvesting:- throughout the year near by water resources.

Madanaphala – Randia Spinoza – Ayurvedic Herb

Madanaphala

Randia Spinoza – Ayurvedic Herb

Madanaphala - Randia Spinoza - Ayurvedic Herb

 

 

In the Vedic literature the thorns of Madana are mentioned and in case of vegetable poison Madanaphala is given to induce vomiting.

 

Charaka quoted it as the best emetic drug and about 133 yogas described with it in the Kalpa sthana . He also emphasized its role as antidote to many poison. It is important to note that Madanaphala is enumerated under Vamana Dravya’s but not under Vamanopaka group. However it’s found in the Asthapanapaka & Anuvasanopaka group. The author is of the view that in the context of Vamana Dravya Madana is pricked up as analogue while in Ashthapana & Anuvasana Dravya its considered as a prodrug. This will be a topic which needs scientific study in the future.

 

Susrutha mentioned that vomiting may be induced even by giving the flower of Madana along with honey and rock salt. Chunekarji quoted Pindara of Bhavamisra as Randia aliginosa.

 

SYNONYMS & INTERPRETATIONS

 

  • Karahataka– That which induces the thorn
  • Kapha vardhana– It removes kapha dosha after it gets aggravated.
  • Galana – Liquification, the thick kapha gets liquefied.
  • Golaphala– Fruit is globose in shape.
  • Chardana– Vomiting
  • Ghandala– Globous shape of fruit.
  • Gharaphala– The ripe fruit has mild ridges.
  • Pindithaka– Fruit is spherical, round or bicular in shape.
  • Marupaka- It grows abundantly. They are visha it is taken excess its poison.
  • Ratha– the plant grow very close to each other .
  • Vamana– Inducing vomiting
  • Vishapushpaka– When taken in excess quantity act as visha.
  • Shalya– Action is compared with fast shalya.
  • Shwasana– It were shwasa Roga.

CONTRAVERSY

 

Madanaphala botanical name is Randia Spinosa. Which belongs to rubiaceae family.

Catunasegan spinosa, Trivengadum veromphis spinosa, Randia Dumetorum these are other botanical names.

But randia spinosa is the used botanical name. Other where only used in olden times.

 

 

VERNACULAR NAMES

 

English : Emetic Nut

Hindi : Mainaphala

Kannada : Karekay

Malayalam : Kara

Telungu : Mranga kaya

Bengali : Mayanaphal

Marathi : Golaphal

Gujarathi : Mindhala

Tamil : Marukkalam

Santhal : Loto

Arabic : Jijul Kai.

 

USEFUL PARTS

 

  • Seed
  • Fruits

 

CHEMICAL COMPOSITION

 

It contains saponin valeric acid resin, wax, and some coloring matter. Besides saponin the fruit contain a new triterpene & acid resin 7 trace of pale essential oil. The presence of pectin mucilage & taetaric acid is reported sapomine is the main acture principle in the fruit with trierpine tanine. The seed contain oil, protein mucilage resin & an alkaloid but is without saponine.

GENUS CHARACTERS

 

Large shrub with strong spines. 1 – 3 cm long branch.

Leaves : 1 -2 inch long obovate, obtuse, wrinkled shining above pubescent .

Fruit: Like a small crabapple yellow colour 1-1.5 inch long pulp.

Seed: Many, flat, embedded in pulp.

Calyx: Companulate, strigose, 0.2 – 0.3 inch long.

Corolla: Lobes spreading , 0.5 – 0.75 inch long .

Androecium : 5 stamen, epipetalous with shout filament.

Gynecium: Bicaepillacy syncaepous infeior bilocular

 

ORGANOLEPTIC STUDY

Colour : Flowers are white yellow in colour.

Taste: Sweet.

Size : 1.3 -3.2 cm long branches horizontal and very short leaves are 1-2 inch long.

 

PROPERTIES AND DOSHAGNATHA

Rasa : Madhura Thiktha

Guna : Laghu, Ruksa

Virya : Ushna

Vipaka : Madhura

Doshagnatha : Kapha vathahara, kaphahara, chardhana.

Prabhava : Vamana

Karma : Vamaka, vathanulomana , Rakthashodhaka, Kaphanissaraka, Lekhana, Medohara, Vranaropana, arthavajanana , vishagna, Nadishmaka, vedhanasthapana.

 

PRAYOGA

Kaphapradhana Vikaras, Jwara, Gulma, Prathishaya, Vibhandha, krimi, kushta, medoraga, visha Pravahika, Udhavartha, udhararoga , Aanaha, gulma, shoola.

 

PHARMACOTHERAPEUTIC PROPERTIES & ACTION

 

The extracts exhibit insectidal & insect repellent properties. They would possibly be used as synergists in insecticidal preparation. Fruits are used in colour intensifier and they are said to produce a yellow pulp. The ethanolic extract of pulp showed a stimulant activity on isolated guinea pig uterus. The fruits are eaten after roasting a cooking.

The fruits are reported to be mixed with stored grain to preserve it from attack of insect and in this way its insecticidal effect is also utilized . The unripe fruit are also used as soap in various areas.

For adhoka raktha pitta Beeja choorna boiled in Yavagu .

Its an emetic agent.

 

PHARMACOTHERAPEUTIC USES

 

Madanaphala irritates the stomach causes vomiting due to its Thiktha Katu Rasa, Ushna Thukshna attributes vyavayi , vikasi, Laghu Guna, Best Vamaka since it does not cause any side effect during emesis. 3-4 g of pulp soaked in 25 ml of warm water for an hour be triturated rinsed through cloth & should be administered on empty stomach with honey saindhava to cause emesis.

 

 

RECENT RESEARCH ADVANCES

In anaesthetized dogs a drug consisting of R.dumatorum in doses of 2,4,8 mg/kg produced hypotension respiratory depression . It produced positive inotropic chrontropic effects on perused frog heart preparation. In isolated rabbit heat it increase pentobaebitone induced hypnosis in mice significantly.

Crude saponin fraction showed hemolytic molluscicidal immunostimulating activities.

 

MATRA

Powder – 3 – 6 gm (Emesis)

Powder – 1- 2 gm (Therapeuties)

 

Vishishta Yoga

 

  • Madhanaphaladhi vati
  • Madhanadi Choorna

Kushta – Saussuria lappa C B Clarke – Ayurvedic Herb

Kushta – Saussuria lappa C B Clarke – Ayurvedic Herb

Kushta - SAUSSURIA LAPPA C B CLARKE - Ayurvedic Herb

 

 

 

LITERARY REVIEW

  • The drug kushta has been mentioned in veda’s.
  • It is claimed to cure several diseases and posses the properties like Rasayana, vrushya and krimigna.
  • It is specifically mentioned as tamaka nashaka(antipyretic).
  • It is climed to posses aroma and important among all the herb, it is used for dhupa.
  • It is agrya aushadhi for upanaha and abhyanga.
  • And it is used as substitute for tagara.

 

SYNONYMS AND INTERPRETATION

Kushtam:-

  • Cures vata rogas.
  • Its root spreads deep in soil and the plant remain firmly fixed.

Kashamiraja:-

  • Grows mainly in kashmira.

Utpala:-

  • It grows near water sources and great altitudes.
  • It flowers resemble those of lotus in shape.

Pakala:-

  • It brings about dasha paka or roga paka easily.

Paribhashya:-

  • It effectively conquer many disease.

Vapya:-

  • Found near wells.

Vyadhi:-

  • It relieves man from many diseases.

 

VERNACULAR NAMES

  • English:- Kuth, costus.
  • Hindi:- kuta, kura.
  • Kannada:- koshta.
  • Malayalam:- kottam simakkottam.
  • Telugu:- changluva-koshtu.
  • Tamil:- koshtam.

 

OFFICINAL PART

  • Root

 

DOSE

  • Powder : 1-2 gm.

 

CHEMICAL COMPOSITION

  • Essential oil.
  • Costol.
  • Taraxas-terol.
  • Costunolide
  • Dehydro costuhactone.
  • Alpha-cyclocostunolide.
  • Sitosterol.
  • Sesquitepenes.
  • Ar-curcumene.
  • isodihydro costuhactone.
  • Costus-lactone.

 

PROPERTIES

  • Rasa:- tikta, katu, Madhura.
  • Guna:- lagu, ruksha, thikshana.
  • Veerya:- ushna.
  • Vipaka:- katu.
  • Doshagnatha:- vata, kaphahara.

 

ACTIONS

  • Lekhaniya.
  • Vrishya.
  • Sukrasodhana.
  • Artavajanana.
  • Stanyajanana.
  • Vedanastapana.
  • Varnya.
  • Arasadaka.
  • Dipana.
  • Sulaprashamana.
  • Swasahara.
  • Mutrala.
  • Jvarghna.
  • Rasayana.
  • Visagna.
  • Rakshogna.

INDICATIONS

  • Kusta
  • Hikka.
  • Kasa.
  • Shvasa.
  • Parshva shoda.
  • Hridroga.
  • Visarpa.
  • Kandu.
  • Vatarakta.

 

THERAPEUTIC USES

External uses:-

Charaka-

Kushta:- dhanyaka and kushta churna is applied as lepa.

Vagbata:-

Arumshika:- kushta is roasted on mud pan till it become back, than it is powdered and strained through a cloth, this is applied on scalp with oil.

Mukhakhanthi vardanaratha:- nimbi swarasa and kushta lepa for 7 days along with honey.

Vangasena:-

Amurshika:- erandamula and kushta in equal part are applied on scalp.

 

 

RESEARCH STUDIES

 

  • Delocalized oil and some lactone fractions of the oil exhibit hypotensive, spasmolytic and brochodilatory effect (chopra,1,958, dutta,1960).
  • Anthlmintic activity of sassurea lappa was established by kokate , in 1986.
  • It is a powder enhanced the aortic prostaglandin, example like activity in experimental rabbits (dwiredi et al 1987).
  • 5 new amino acid sesquiterpene adducts,sausurecemines A.B.C.D.E.F were isolated from the root.(yoshikawa et al,1993)
  • The aqueous extract was administered orally and the effect was compared to cofiibrate. The lipid lowering properly was highly significant(p>0.001). (upadhyay,1994).
  • It has shown significant effect in reducing blood sugar level of obese diabeties.

 

FORMULATIONS

  • Kushtadi churna.
  • Kushtadi thaila.
  • Kushta rasayana.
  • Kushtadi kvatha.
  • Kushtadi prakapa

KRISHNAJEERAKA – Black caraway – Ayurvedic Herb

KRISHNAJEERAKA – Black caraway – Ayurvedic Herb

 

KRSNAJEERAKA Linn

 

 

Krishnajeeraka is as famous as Jeeraka in the Ayurvedic texts since Sushrutha mentioned Jeeraka dravya.

Chakrapani commented that Karvi means Krishnajeeraka.

Charaka described it as rochana and pachana in nature. Krishnajeeraka is mainly indicated for jeernajwara(Chrinic fever) and grahani disorders.

 

SYNONYMS

Krishnajeeraka:- The seeds resemble like jeeraka and black in colour.

Sugandha:- Having pleasant smell.

Udarashodan:- That which relieves udara or belching by its deepan action.

Jarna:- Having deepan property.

Kanajeeraka:- Same like jeeraka grain.

Kasmirjeeraka:- Grows in Kashmir.

Varshakali/Kalapeshika:- The seeds having black colour.

Bahugand:- Strong aromatic smell.

Bedini:- Having bedini property.

Ruchya:- Improve taste

Nila/Nilakana/Varnakali:- The grains are dark in colour

Danta shodini:- Useful in dental diseases

Hridva: Useful in heart diseases

Kalajeeraka:- Like jeeraka but black in colour

 

TYPES OF KRISHNAJEERAKA

Certain Nighantu works described:

 

Six varieties

Shwetajeeraka

Peethajeeraka

Krishnajeeraka

Sukshmajeeraka

Sthulajeeraka

Vanajajeeraka

 

VERNACULAR NAMES

 

Sanskrit: Krishnajeeraka

Hindi: Kalajeera

Kannada: Karijireege, Shahajirige

Tamil: Karamjeeragam,Shimaishambu

Telugu: Nallajeelalkara

Malayalam: Karunjeeraka,Karinjeerakam

English: Black caraway, Black cumin, Indian caraway

Bengali: So-jeera

Persian: Jeerya-riza, Zira

Marathi: Jeere

Arabilc: Kamuna,Karum-aswad

Espernato: Karvio

Francais: Carvi

Gujarati: Shahijeerum

Hornjoserbsce: Kirnjeleka

Italiano: Carvi

Kashmiri: Krihunzur

Kurdi: Jaj

Latina: Carecum,

Latviesu: Plavas Kirnene

Magyar: Kormerry

Nederlands: Karwij

Norsk: Karve

Origa: Kalajira

Polski: Krninek Zwyezajrry

Portugues: Alcaravia

Punjabi: Zira Siyah

Roman: Chirnan

Shquip: Qumnoni

Slovencina: Rasca, Kumina

Suomi: Kumina

Svenska: Kummin

Urdu: Zira siyah,Kalajeera

Veneto: Kumo

 

PROPERTIES

Rasa: Katu

Guna: Ruksha

Veerya: Ushna

Vipaka: Katu

Doshakarma: Kafavathashamaka

 

PHARMACOLOGICAL ACTION

Dhanwanthari nighantu Raja nighantu Madhanapala nighantu

Ruchya Gulma Sangrahi

Ajeerna Adhmana Medhya

Jwaragna Athisara Garbashayavishudhi

Chakshushy Grahni Adhmana

Krimi Chardhi

Gulma

 

THERAPEUTIC USE

Mukhapaka: Krishnajeeraka,Kushta and indrayava are to be

chewed together for three days (Yogaratnakara)

Vishamajwara: Krishnajeeraka should be given with jaggery.

(Bhavaprakasha)

Pratishyaya: Krishnajeeraka is packed in a piece of cloth and

used for smelling in case of cold/nasal obstruction.

(Vangasena)

The Arka prepared from krishnajeeraka is used in children to relieve the vatha in abdomen.

Malarial fever: In take of krishnajeeraka with equal quantity of

jaggery and a bit of Maricha. (Bhavaprakasha)

Krishnajeeraka is also used as an anupan for other medication.

The oil is used to give pleasant smell for other medicines.

 

The kavatha prepared out of krishnajeeraka is used for givening fomentation in inflammation of Arshas. In vishamajwara krishnajeeraka is given with equal quantity of Guda. The fruits are useful as stomachic,carminative and lactagogue. It is abortifacient, antihelmenthic, aromatice, astringent, cardiac, lactogogue, purgative stimulant, stomachic and tonic. It is a flavouring agent, it is one of the ingredients in curry power, they have powerful odour and flavor. They are useful in amenorrhea, blood. Omitting with bile, general debility and dyspepsia, it is useful and eye wash for strengthening vision.

It is given in intermittent fever, painful swellings and protruding piles, it is used inrheumatism and worms. The seeds with sugar and jaggery mixed with a bit of maricha are given in malarial fever. The seeds mixed with other suitable drugs drugs and vehicles are given to check all types of anorexia.

PART USED

  • FRUIT
  • SEED

 

DESCRIPTION OF THE PART

Oblong, laterally compressed and slightly curved fruits upto 5.mm long and 1.5mm broad. Tapering towards both ends. The mericarp is yellowish brown in colour and shows five equal sides with five narrow ridges which are very distinct, endosperm brown and somewhat oily.

Odour:- Characteristic

Taste:- Pungent.

 

DOSAGE

Choorna: 1-3 grams

 

FORMULATIONS

Jirakady arista –Bhaishajya ratnavali Sutika roga vikara

Jirakadi modaka-Yogagrantha

Yogaraja guggulu-Bhaishajya ratnavali Aamavatadikara

Ashtachoorna-Ashtanga Hrdaya Gulma chikitsa

Krshnajeeraka taila

Soubhagya shunti choorna

 

CHEMILCAL CONSTITULENTS

Seeds: Essential oil, triacylglycerols, sterols petroselinic acid etc.

 

Eeesential oil: Carvone, lilmonene, germacrence –D

Belemenle, P-cymene, cuminal trans-and

cis-carveol, carveol etc.

 

The dried and crushed seeds on steam distillation gave a pale yellow to light brown essential oil (known as CARWAY OIL) with a strong aromatic odour, carvone and limonene are the chief constituents of the oil and is odour and flavor are mainly attribuded to them.

 

MODERN PHARMACOLOGY

Caraway in British pharmacopy and Indian Pharmacopy drug. Caraway is an aromatic carminative used as caraway water in the treatment of flatulent colic of infants. Caraway water is suitable vehicle for childrens mixture.

 

FLOWERING AND FRUITING TIME

Rainy season, autumn and cold seasons,

Winter season crop.

 

CULTIVATION

(Preparation for market)

 

Caraway does best when the seeds are sawn in the autumn, as soon as ripe, though they may be sawn in March, sown in drills, one foot part, the plants when strong enough, being thinned out to about 8 inches in the rows. The ground will require an occasional hoeing to keep it clean and assist the growth of plants. From an autumn sown crop, seeds will be produced in the following summer ripening about August.

When the fruit ripens the plant is cut and the caraway are separated by threshing. They can be dried either on trays in the sun or by very gentle heat overa stove, shaking occasionally. There are several varieties the English, Duch and German (obtained from plants extensively cultivated in Moravia and Prussia) and other varieties imported from Norway, Finland, Russia and the Morocco ports.

 

SUBSTITUTES AND ADULTERANTS

Fruits of Bunium persicum (Boiss) Fedt. Syn carum bubocastamum Koch known as Kalazira or shimai shiragam is commonly used as substitute. The fruits of this species are larger in size (upto 7 mm long and 2mm. wide) darker in colur seminterete in shape and carvy a heavy spicy odour. The two ventral vittae in Bunium persicm are of carum carvi, where dorsal and ventral vittae are of the same size coloured fruits of cumini cynimu inn are sometimes found as adultrants in commercial samples.

 

RESEARCH

Carveol showed antihistaminic and antianaphylasctic effects in guinea pigs (Zhejiang yike Daxue xacbow 1988, 17, 115).

 

CONTROVERSIAL STUDIES

P.V.Sharmaji considered carum carvi as Karavi and

C.Bulbocastanum as krishnajeerak. Bapalalji also accepted carum carvi as Karagi (krishnajeeraka). Dr.Nishteshwar.K. mentioned C.carvi as krishnajeeraka in his text . Thakurji quoted C.cyminum and C. carvi as shwetha and Krishna varieties of jeeraka, prithvika as C. bulbocastanum and Nigella sativa as Upakwncika. This school appears to be more appropriate and relevant.

 

DRUG BIOAVAILABILILTY ENHANCING ACTIVITY

A chemically standardized butanolic fraction of carway seeds enhanced the plasma level of three anti tubercular drugs. Rifampicin (RIF), pyrazinamide (PZA) & Isoniacid (INH), when co-dosed in combination with rat. In the presence of the herbal fraction of carway, C max & AVC of RIF where enhanced by 63% & 53%, for PZA it was 57% & 35% & for INH – 40% & 25%. It is due to penneating enhancing effect of carway.

KHADIRA – Acacia catechu – Ayurvedic Herb

KHADIRA – Acacia catechu – Ayurvedic Herb

khadira
khadira

Khadira

According to Rgveda, khadira is one of the important trees both of rituals and medicinal usage. It is described with the synonym ‘ vibadha. Its heartwood is considered to be very strong and is used as wedge while manufacturing chariots. Satapatha Brahmana mention it as one of the strongest trees and strength of its stem is simile to the bone in strength. Khadira was used as fire wood and as vessel / container. The extract of heartwood [khadirasara] is used for external wearing like precious stone. Ayurvedic texts quote Khadira twing as the best among the tooth brush which is kasaya [astringent] in taste. The original Khadirasara is the natural secretion [ gum resin] of the matured / old trees of Acacia catechu which is black in colour. But nowa days the dried extract of heartwood is considered as Khadirasara.

Ayurvedic Herbal Medicine – Khadira

You may be wondering what Ayurveda says about Khadira. Read on to learn more about its Morphology and medicinal properties. Then, decide whether or not it is the right herbal supplement for you. In addition, you’ll discover what Khadira does and how to use it. Once you’ve finished reading this article, you’ll be well-equipped to decide whether or not it is the right product for you.

What Ayurveda says about Khadira

If you are unfamiliar with Ayurveda, you might be surprised to learn that one of the most commonly used herbs is the Khadira tree, also known as Acacia catechu. The tree, which grows abundantly in India, is an excellent medicinal plant, with many uses. In Ayurveda, khadira is used for a variety of ailments, from cutaneous infections to horses.

While the herb is considered a safe food in Ayurveda, there are a few risks involved in using it. For instance, it may cause allergic reactions in some individuals. If you suspect you may have an allergy, you should speak to your doctor. Another potential danger is consuming too much of the herb. It may cause inflammation and ringworms, so if you are unsure of what to take, seek medical advice.

Medicinal benefits of Khadira include relieving malabsorption and indigestion. Khadira decoction is recommended for use in baths and beverages. The heart wood extract can be used for mouth gargles. It is beneficial for stomatitis and gingivitis. There are many other benefits of the tree, but for most, it is an excellent cure for many diseases and skin disorders.

LITERARY REVIEW

Charaka described it as the best drug for Kustha. Kusthaghna term is used by charaka at once [ C.S.Ci, 23/ 53 ] But it is considered to be Cakramarda. Gayathi is the synonym used by susruta and vagbhata. Another name Balapatha was mentioned by Vagbhata alone [ A.H. Ut. 39/105]. In one context susruta described ‘Gayatrya’ denoting one of the varieties of some but not Khadira [ S.S. Ci. 29/7, 31]. Vagbhata emphasized its utility as tooth brush. Cakradatta describes khadira in the treatment of svarabheda. In paippalada samhita, it is specifically quoted in the treatment of kilasa and visa roga.

SYNONYMS

Khadirah : Relives the diseases and gives strength to the body.

Raktasara : The heart wood is red in colour.

Gayatri : The wood is regarded as holy.

Dandadavana : The twigs are used as tooth brush .

Khandaki : Having thorns

Balapatra : The leaves are small

Bahushalya: Having many thorns.

Yanjiyah : Wood is used for holy fire.

Kushtaghna : Specific drug in the treatment of kustha.

Saradruma : The heart wood is strong and woody.

Galaroganuth : Useful in throat disorders.

Jihwasalya : The spines are curved.

Medoghna : Efficacious in obesity.

VERNACULAR NAMES

  • Sanskrit Name : Khadira
  • Hindi Name : Khair
  • English Name : Catechu tree
  • Malayalam Name : Karingali
  • Tamil Name : Karungali
  • Kannada Name : Kachu
  • Telugu Name : Chandra

PARTS USED

  • Extract
  • Bark
  • Wood
  • Flowering tops
  • Gum

MATHRA

  • Churna – 3 to 5 gm
  • Kwatha – 50 to 100 ml
  • Kadira sara – 400 mg to 1 gm

Morphology of Khadira

The Khadira tree has an impressive morphology. It is a moderate-sized deciduous tree with grayish-brown bark. The leaves are green with 50 pairs of leaflets. The leaves are bipinnate and compound, with a midriff that contains secretory structures. Khadira flowers are five to ten centimeters in diameter and pale yellow or green in color. They are enclosed in bell-shaped calyxes. Khadira fruit is oblong and glabrous, and the seed pod is smooth and dark brown.

The tree is native to India, Pakistan, Bangladesh, and Thailand. It grows up to 1200 metres in altitude. It is native to mixed deciduous forests and is commonly found in hills and lower mountains. It grows well in sand. Its botanical name, Acacia catechu, comes from the Greek word acacia, which means barb or cutch. The tree yields a tannin extract called khadira, which has medicinal properties.

The methanol extract of Khadira has been extensively studied for its antimicrobial properties. This extract inhibits the growth of both pathogenic and non-pathogenic bacteria. The resin is also used as a topical skin treatment. In addition to its medicinal use, the khadira tree is a source of many other Ayurvedic drugs. Khadira’s heartwood has many medicinal uses, including as a blood purifier and inflammation-relief agent.

GROWTH AND MANAGEMENT

Cutch tree prefers subtropical or tropical open woodlands and grasslands. Early growth is slow, and it grows well on most soils, but well drained, shallow to medium – depth sandy soils suit it best. Cutch tree reproduces by seed. It will also report from the base if the main stem is removed and the cut stamp is not treated with herbicide.

Weeding is essential, especially when the plants are still young. Protection against fire is necessary, especially in the drier parts of its range and so is protection from grazing animals.

Pests and Diseases:

Parasitic plants of the genus cascuta may kill the plant, and hemiparasitic plants of the genus Loranthus may damage trees. Rodents are also reported to damage the trees.

OTHER BENEFITS

  • The pale yellow mucilaginous gum from Khair is said to be of very good quality and is regarded as the best substitute for true gum Arabic.
  • The wood extracts are used for tanning and dying khaki.
  • The wood being hard is used for making rice pestles, ploughs, handles for knife and rollers for crushing sugar cane and oil seeds.

ECOLOGY

Acacia catechu occurs naturally in mixed deciduous forests and savannas of lower mountains and hills. It is especially common in the drier regions on sandy soils of riverbanks and watersheds. The species grows in a code range of soils such as sandy, gravelly alluvium, loan with varying proportions of sand and clay and black cotton soils. It is capable of growing in shallow soils.

VARIETIES

  • In the samhitas, 2 varieties are mentioned.
  1. Khadira
  2. Kadara
  • In Dhanvantari Nighantu, 2 varieties are mentioned.
  1. Khadira
  2. Somavalka
  • In Raja Nighantu, 5 varieties.
  1. Khadira
  2. Somavalka
  3. Tamrakantaka
  4. Vitkhadira
  5. Arimeda
  • In Amarakosa mentioned 3 varieties.
  1. Khadira
  2. Vitkhadira
  3. Somavalka
  • In Nighanta Ratnakaram
  1. Valli Khadira
  • Bhavamisra Quoted:
  1. Khadira
  2. Kadara
  3. Irimeda

Medicinal benefits of Khadira

Many women have found that the herbal medicine known as Khadira has beneficial effects on their health. It is known to be an excellent uterine tonic and can treat various types of menstrual problems including leucorrhoea and menorrhagia. It can also be effective in healing ulcers and wounds in the anal and vaginal mucosa. Khadira can be taken as a decoction and applied topically to wounds. Khadira’s leaves and flowers are used for making paste for treating skin eruptions and other ailments.

Among its medicinal benefits, Khadira increases circulation to the joints, skin, and lymph nodes. It also inhibits the release of inflammatory cytokines, which lead to damage to tissues and increase joint stiffness. Khadira’s biological roots are in the ancient Ayurvedic literature. It is mentioned in the Vedic period, the Rigveda, and the Atharveda. It is also found in the Mahabharata and the Ramayana. The plant’s bark is dried and ground into a powder, and it contains alkaloids, tannins, flavonoids, and triterpenes.

Although many health experts support the benefits of Khadir, there are some risks to it. Khadir may cause allergic reactions in some people. If you have an existing allergy to Khadir, you should seek the advice of a qualified physician before beginning the herb. It may also lead to minor side effects like inflammation and ringworm. Despite these benefits, you should consult with a nutritionist or physician before taking Khadir for any length of time.

CHEMICAL CONSTITUENTS

Heart wood:

  • The main constituent of the heartwood are catechin and catechutanic acid.
  • The catechin content varies from 4 to 7 % . The catechin of Acacia catechu, also called acacatechin, is a colorless crystalline material insoluble in cold water but soluble in hot water.

Wood:

Wood contains α- β-, γ- Catechin, i- epicatechin, (+) – Afzelchin, gossypetin, procyanidin Ac and Taxifolin.

Gum:

Gum contains L- arabinose, D- galactose, , D- rhamnose.

PROPERTIES

Rasa – Tikta, Kasaya

Guna – Laghu, Ruksa

Virya – Sheetha

Vipaka – Katu

Prabhava – Kusthaghna

DOSHAGNATHA

  • Kapha – Pittahara.

KARMA

  • Kusthaghna
  • Rucikara
  • Stambana
  • Rakta sodhaka
  • Sothahara
  • Kaphanisaraka
  • Sukrasodhana
  • Kandughna
  • Jwaraghna
  • Medohara
  • Krimighna
  • Dantya
  • Raktastambana
  • Grahi
  • Kasaghna
  • Vranaropana
  • Mutra sangrahaniya

PRAYOGA

  • Kandu
  • Kasa
  • Aruci
  • Krimi
  • Prameha
  • Jvara
  • Svitra
  • Sotha
  • Pandu
  • Vrana
  • Danta roga
  • Arshas

THERAPEUTIC USES

  • Kushta : In food and drinks, bath, fumigation, and external applications vidanga, the antihelmintic and khadira, the antileprotic are outstanding .
  • Prameha: In sanairmeha, decoction of khadira and in madhumeha, decoction of Khadira and kramuka are useful.
  • Diseases of teeth : Decoction of khadira root heals the diseases of teeth.
  • Bhagandhara : Decoction of khadira and triphala is enriched with ghee and powder of vidanga is given orally.
  • Slipada: Kalka of Khadira sara, Bijasara, sala sara is mixed with honey and given with gomutra in the morning.
  • It is useful in relaxed condition of the throat, mouth and gums, also in cough and diarrhoea.
  • Externally it is employed as an astringent and as a cooling application to ulcers, boils and receptions on the skin.
  • Svitra: Internal and external use of khadira kasaya is useful.
  • Juice of the fresh bark is used along with asafetida in haemoptysis.
  • Being astringent and haemostatic, powder is used in wound healing and in dental conditions.
  • Due to its astringent properties, it acts as a spermicidal and is used as a uterine tonic. It is also used in leucorrhoea and menorrhagia.
  • A mixture of flower tops, cumic, milk and sugar is useful in gonorrhea.

RESEARCH STUDIES

  1. A flavonoid isolated from ethonolic extract of central wood of Acacia catechu showed hypoglycaemic activity. (Chakravarthy et at, 1983).
  2. Cyanidanol (+), the active principle of Acacia catechu failed to prevent the acute type of hepatitis induced by heavy single does of CCl4 in rats. The chronic type of damage induced by multiple doses of CC14 was, however, prevented (Rege ct at. 1984 b).
  3. Seeds exhibited marked hypoglycaemic activity in normal rats but not in alloxan – induced rats (I.J. M.R. 19760
  4. The ethyal acetate extract of Acacia catechu is reported to possess hepatoprotective activity (Jayasekhar, et at, 1997).
  5. It was tried in the management of lepromatous leprosy (Ojha et al., 1969)

VISHISHTA YOGA

  1. Khadirarista
  2. Khadiradi kwatha
  3. Khadirastaka
  4. Khadiradi vati
  5. Khadirakalpa
  6. Khadiradi tailam
  7. Mahakhadiradya ghrta
  8. Arimedadi taila.